Sensitive detection of mitochondrial structural alterations on simulated data

2018-06-28T04:54:54Z (GMT) by Swaraj Basu Erik Larsson
<p>Testing three different sensitive sequence aligners (BLAT, BLASTn, LAST) on simulated data generated from reference human mitochondrial genome along with genomes with a deletion and a duplication.  The aim is to identify the aligner best suited for detection of large structural alterations in the mitochondrial genome.</p>