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Selection pipeline for miRNAs of interest and finding miRNA-gene interactions in TCGA.
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posted on 2016-12-13, 18:57 authored by Jeremy T-H. Chang, Fan Wang, William Chapin, R. Stephanie HuangA) Selection pipeline to identify clinically relevant miRNAs in breast cancer. Expression data for miRNA and overall survival data (rectangular shapes) were obtained from TCGA breast cancer dataset. Intermediate lists (trapezoid shapes) and findings (oval shapes) derived from our TCGA analysis. B) Selection pipeline to discover possible miRNA-gene interactions. Data retrieved from other sources (rectangular shapes) were obtained from TCGA or miRDB. Intermediate lists (trapezoid shapes) and findings (oval shapes) derived from our analysis.
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5Asurvival-associated genes RAD 512DUBESTAGpatient survivalgene expressionBreast Cancer Prognosis MarkersmiR -320a miR -361-5p miR -21-5p miR -103amiR -361-5p targets ARCN 1TCGA1BmiRNA target prediction analysisCancer Genome Atlas Breast cancerRMNDRRPmiR -320a targetsTDGmiRNA expressionhsa-miRmiR -21-5p targets MSH 2miR -320a miR -361-5pCancer Genomes Atlasbreast cancer survival
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