Select chromosome-wide scans for epistatic effects in GEUVADIS data set.

Depicted are the −log₁₀(P) transformed MAPIT p-values of quality-control-positive cis-SNPs plotted against their genomic position in chromosomes (A) 1, (B) 6, and (C) 22, respectively. Note that MAPIT was implemented with K_cis. Here, the epistatic associated genes are labeled (blue). The (red) horizontal line indicates a genome-wide significance threshold (P = 1.828 × 10⁻⁸). Note that all panels are truncated at −log₁₀(P) = 10 for consistency and presentation, although for some genes there are strongly marginally epistatic associated markers with p-values P ≈ 0.