jo701982m_si_001.pdf (2.57 MB)
Rhodium Fluorapatite Catalyst for the Synthesis of Trisubstituted Olefins via Cross Coupling of Baylis−Hillman Adducts and Arylboronic Acids
journal contribution
posted on 2008-01-04, 00:00 authored by M. Lakshmi Kantam, K. B. Shiva Kumar, B. SreedharTreatment of fluorapatite (prepared by incorporating basic
species F- in apatite in situ by coprecipitation) with an
aqueous solution of RhCl3 resulted in rhodium-exchanged
fluorapatite catalyst (RhFAP), which successfully promoted
cross coupling of Baylis−Hillman adducts with arylboronic
acids to yield trisubstituted olefins. A variety of arylboronic
acids and Baylis−Hillman adducts were converted to the
corresponding trisubstituted olefins, demonstrating the versatility of the reaction. The reaction is highly stereoselective.
RhFAP was recovered quantitatively by simple filtration and
reused with almost consistent activity.