Relationship between Kellgren–Lawrence grading (KL), joint space width (JSW) and biochemical markers

<p><b>Copyright information:</b></p><p>Taken from "Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis"</p><p>Arthritis Research & Therapy 2004;6(3):R208-R212.</p><p>Published online 12 Mar 2004</p><p>PMCID:PMC416443.</p><p>Copyright © 2004 Takahashi et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.</p> Pyridinoline (Pyr) level is expressed as nmol/mmol creatinine. There were significant relationships between joint space width (= 0.003), pyridinoline (= 0.034) and TIMP-1 (= 0.017) determined with the Kruskal–Wallis test. Bars indicate maximum and minimum values within the observation range. values are shown in each panel; N.S. indicates not significant. CRP, C-reactive protein; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinases.