Quantitative changes in the sequential thrombus formation area measured with optical coherence tomography.

(a) Thrombus formation at the interface between the connectors and the tube in the blood circulation test. The white arrow indicates the thrombus area, red lines represent the connectors, and yellow lines represent the location of the tube. The data represent one of the six tests shown with blue square plots in (b) and (c). (b) Thrombus formation area at the interface between the inlet of the connector and the tube. The tests were performed six times using porcine blood collected from six different individuals. (c) Thrombus formation area at the interface between the outlet of the connector and the tube. The right sides of (b) and (c) show the areas of thrombus formation detected by OCT after replacing blood with saline solution.