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Principal component analysis of study participants compared to HapMap ethnic groups.

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posted on 2017-07-10, 18:24 authored by Matthew J. Magee, Yan V. Sun, James C. M. Brust, N. Sarita Shah, Yuming Ning, Salim Allana, Angela Campbell, Qin Hui, Koleka Mlisana, Pravi Moodley, Neel R. Gandhi

Principal component analysis of study participants compared to HapMap ethnic groups.

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    Results Genomic analysesantimicrobial peptide cathelicidinAffymetrix Axiom Pan-African ArrayVDR SNPsvitamin D receptorvitamin D receptor gene25- hydroxyvitamin D91 MDR TB subjectsmultidrug-resistant tuberculosis patientsVDR genesputum culture conversionDNAdecrease culture conversion rates121 VDR SNPsadult MDR TB patientsIQRSouth Africa Background Vitamin D modulatesMDR TB patientsHIVSNP rs 74085240culture conversionsecond-line TB treatment

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