Predicted binding affinity change between two alleles of SNP rs12740374 (T/G).

The color in each cell represents the predicted binding affinity of allele G minus that of allele T for the corresponding TF and cell line. The number in each cell of the heatmap is the number of ChIP-seq datasets in the training set for the corresponding TF and cell line. If TFImpute predicted strong binding in the minor allele but no binding in the major allele, the score was 1. If TFImpute predicted no binding difference between the two alleles, the score was 0.