Fig 1.tif (479.33 kB)
Preconditioning with CoCl2 is more effective than intermittent clamping (IC).
figure
posted on 2017-07-07, 17:42 authored by Kenny Rao, Kapil Sethi, Joseph Ischia, Luke Gibson, Laurence Galea, Lin Xiao, Mildred Yim, Mike Chang, Nathan Papa, Damien Bolton, Arthur Shulkes, Graham S. Baldwin, Oneel Patel(A) Experimental design for the in vivo study comparing the ability of different preconditioning techniques to protect against IRI in rats. (B) Animal sickness scores in rats treated with saline (control) (●), 30 mg/kg CoCl2 (■), IC (⬢) or IC + CoCl2 (▲). (C) Serum creatinine concentrations (mean ± SEM (µmol/L)). The rise in serum creatinine was less in rats preconditioned with 30 mg/kg CoCl2 than in the saline control group. (D) Serum urea concentrations (mean ± SEM (mmol/L)). *p<0.05 Vs saline treated control.
