figshare
Browse
Boonlom_Thavornyutikarn-Monash University-the final version.pdf (10.43 MB)

Porous 45S5 Bioglass Scaffolds for Bone Tissue Engineering

Download (10.43 MB)
thesis
posted on 2017-12-12, 23:18 authored by BOONLOM THAVORNYUTIKARN
Scaffold-based tissue engineering approaches have gained considerable attention in bone regeneration. This thesis has focused on development and fabrication of a superior mechanically robust, bioactive and osteoinductive bone scaffold from 45S5 Bioglass or developed partially pre-sintered bioglass using advanced scaffolding technique, such as stereolithography to achieve near-net shape forming, with understanding how the surface chemical reactions of the bioglass when exposed to biological body fluids to control the pH change required for the appropriate in vitro biological responses, and with the added therapeutic agent, such as the anti-resorptive alendronate drug, to enhance bone formation and inhibit bone resorption for the treatment of bone-related diseases.

History

Campus location

Australia

Principal supervisor

Terence W. Turney

Additional supervisor 1

Bryce Feltis

Additional supervisor 2

Paul F.A. Wright

Additional supervisor 3

Kriskrai Sitthiseripratip

Year of Award

2017

Department, School or Centre

Materials Science and Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering