Fig 4.tif (171.41 kB)
Plasma corticosterone at expression.
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posted on 2017-04-21, 17:29 authored by Emilia M. Lefevre, Gregory A. Medley, Timothy Reeks, Suzy Alexander, Thomas H. J. Burne, Darryl W. EylesPlasma corticosterone levels at the expression phase. All groups (n = 12) were habituated to the chamber for 30 min prior to receiving a challenge injection of MK-801 at T0. Corticosterone levels were unaltered by any prior treatment either at baseline (T-30) or 60min after MK-801 challenge (T60). Corticosterone levels did not significantly increase from baseline and were not affected by prior induction treatment of RU486 or MK-801. Data are presented as the mean ± SEM.
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MK -801. RU 486behavioural sensitisation Stressnucleus accumbens tissueGRSprague Dawley ratsnucleus accumbens tissue levelsexpressionNMDA receptor antagonist MK -801.MK -801 injectionsHVAMK -801-induced sensitisationinduction phaseglucocorticoid receptor antagonist RU 486plasma corticosterone levelsDOPACRU 486locomotor sensitisationDMSOMK -801 administration locomotor sensitisation paradigmMK -801
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