jf100108c_si_001.pdf (73.29 kB)
Phytotoxic Activity of Quinones and Resorcinolic Lipid Derivatives
journal contribution
posted on 2010-04-14, 00:00 authored by Cassia S. Mizuno, Agnes M. Rimando, Stephen O. DukeOn the basis of the reported phytotoxic activity of sorgoleone and resorcinolic lipids identified from the root extracts of Sorghum bicolor, 8 resorcinolic lipid derivatives and 10 quinones with various side chain sizes were synthesized. The phytotoxicity of the compounds was tested against a monocot and a dicot species. The quinones were phytotoxic, whereas the resorcinolic lipids were not. Of the quinones, 2-hydroxy-5-methoxy-3-pentylcyclohexa-2,5-diene-1,4-dione, having a five-carbon side chain, showed phytotoxic activity similar to that of natural compound sorgoleone.