Phosphorus-Containing Bis-allenes: Synthesis and Heterocyclization
Reactions Mediated by Iodine or Copper Dibromide

Essid, I.; Laborde, C.; Legros, F.; Sevrain, N.; Touil, S.; Rolland, M.; Ayad, T.; Volle, J.-N.; Pirat, J.-L.; Virieux, D.

doi:10.1021/acs.orglett.7b00648.s002

ol7b00648_si_002.pdf (9.91 MB)

Phosphorus-Containing Bis-allenes: Synthesis and Heterocyclization Reactions Mediated by Iodine or Copper Dibromide

journal contribution

posted on 2017-03-29, 21:13 authored by I. Essid, C. Laborde, F. Legros, N. Sevrain, S. Touil, M. Rolland, T. Ayad, J.-N. Volle, J.-L. Pirat, D. Virieux

Bisphosphorylallenes were easily obtained in multigram scale from the Wittig-type rearrangement of bispropargyl alcohols. Unlike other conjugated bis-allenes, these reagents underwent a double cyclization mediated by iodine or copper dibromide leading to the formation of bis-1,2-oxaphospholenes.