Pesce Variation Regulation Screen

This tab-deliited text file is a list of 1141 S. cerevisiae strains, each with a single deletion of a non-essential gene. For each strain, identified by its deleted gene, we recorded flow cytometric measurements from two fluorescent reporters, one driven by the constitutive ACT1 promoter, the other by the pheromone-inducible PRM1 promoter. We combined these measurements to obtain the average strength of signaling (up to and including transcription initiation) and the variation in that signaling strength. We made these measurements at a weak (0.6 nM) and a saturating (20 nM) pheromone dose.