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Pd-Catalyzed Enantioselective C–H Iodination: Asymmetric Synthesis of Chiral Diarylmethylamines

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journal contribution
posted on 06.11.2013 by Ling Chu, Xiao-Chen Wang, Curtis E. Moore, Arnold L. Rheingold, Jin-Quan Yu
An enantioselective C–H iodination reaction using a mono-N-benzoyl-protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

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