Pathways overlapping between transcriptomic and metabolomic data.

Checkmarks signify significant pathway perturbation in metabolomic data (p<0.05), pink shading denotes enrichment for upregulated genes in that pathway in CS-exposed mice; blue shading indicates enrichment for downregulation in CS-exposed mice (FDR≤0.10). Perturbations indicated by shaded fields under the “Cessation” column persisted following cessation when compared to AC mice.