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Final_Lacey_thesis_Pathogenomics_of_necrotic_enteritis_assocaited_Clostridium_perfringens.pdf (5.5 MB)

Pathogenomics of Necrotic enteritis associated Clostridium perfringens

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thesis
posted on 2018-03-18, 22:51 authored by JAKE AIDAN LACEY
The bacterial pathogen, Clostridium perfringens, causes necrotic enteritis, an intestinal disease of chickens. This disease is of concern to the global poultry industry. C. perfringens can also cause diseases in other animals, including humans. In this thesis, the genetic structure of a collection of C. perfringens strains was analysed and correlated with the different abilities of these strains to cause disease. It was established that significant genetic differences exist between strains and that transfer of genes between bacteria may contribute to the emergence and spread of new virulent strains of bacteria.

History

Principal supervisor

Dena Lyras

Additional supervisor 1

Robert Moore

Additional supervisor 2

Priscilla Johanesen

Year of Award

2018

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Microbiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences