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Partial Identification of the Average Treatment Effect Using Instrumental Variables: Review of Methods for Binary Instruments, Treatments, and Outcomes

Version 2 2018-07-25, 20:42
Version 1 2018-06-05, 21:01
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posted on 2018-07-25, 20:42 authored by Sonja A. Swanson, Miguel A. Hernán, Matthew Miller, James M. Robins, Thomas S. Richardson

Several methods have been proposed for partially or point identifying the average treatment effect (ATE) using instrumental variable (IV) type assumptions. The descriptions of these methods are widespread across the statistical, economic, epidemiologic, and computer science literature, and the connections between the methods have not been readily apparent. In the setting of a binary instrument, treatment, and outcome, we review proposed methods for partial and point identification of the ATE under IV assumptions, express the identification results in a common notation and terminology, and propose a taxonomy that is based on sets of identifying assumptions. We further demonstrate and provide software for the application of these methods to estimate bounds. Supplementary materials for this article are available online.

Funding

This work is supported in part by grants from NIH (R01 AI102634; DP1 ES025459; R01 AI112339; R01 AI27271), ONR (N00014-15-1-2672), and NWO/ZonMW (Veni personal grant 91617066).

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