ol6b02300_si_001.pdf (6.06 MB)
Palladium/Lewis Acid Co-catalyzed Divergent Asymmetric Ring-Opening Reactions of Azabenzonorbornadienes with Alcohols
journal contribution
posted on 2016-09-28, 16:07 authored by Fan Yang, Jingchao Chen, Jianbin Xu, Fujie Ma, Yongyun Zhou, Madhuri Vikas Shinde, Baomin FanBy fine tuning the
combinations of chiral palladium catalysts and
Lewis acids, both the additional and reductive asymmetric ring-opening
reactions of azabenzonorbornadienes with alcohols were accomplished
with good chemoselectivity, regioselectivity, and enantioselectivity.
It was proven that the reductive ring-opening products were generated
through a transfer-hydrogenation process with alcohols as hydrogen
source.