ol7b02704_si_002.cif (292.46 kB)
Palladium-Catalyzed [5 + 2] Cycloaddition of Vinyloxiranes with Sulfamate-Derived Cyclic Imines To Construct 1,3-Oxazepine Heterocycles
dataset
posted on 2017-11-18, 20:29 authored by Yang Wu, Chunhao Yuan, Chang Wang, Biming Mao, Hao Jia, Xing Gao, Jianning Liao, Feng Jiang, Leijie Zhou, Qijun Wang, Hongchao GuoPalladium-catalyzed [5 + 2] cycloaddition
of 2-aryl-2-vinyloxiranes
with sulfamate-derived cyclic imines is described. The zwitterionic
allylpalladium intermediates act as five-membered synthon to react
with sulfamate-derived cyclic imines to furnish [5 + 2] cycloaddition,
giving 1,3-oxazepine derivatives in moderate to excellent yields with
excellent regioselectivities.
