PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas - Fig 5

<p>Pan-cancer NN analysis highlights PDGFRβ as a potential CAF marker in multiple cancer types A. Heatmap of average pairwise Kolmogorov-Smirnoff (KS) D statistics using the top 50 genes in the collagen NN cancer analysis of each of 11 cancer types. <b>B</b>. Venn diagram of top 50 genes in collagen NN ranked list within the five most closely related cancers (based on the average KS D statistic; Fig 5A). Core overlap has 11 genes, which includes PDGFRβ, highlighted in red. ACC: Adrenocortical carcinoma; BLCA: Bladder urothelial carcinoma; COAD: Colon adenocarcinoma; KIRC: Kidney renal clear cell carcinoma; LAML: Acute myeloid leukemia; LIHC: Liver hepatocellular carcinoma; LUAD: Lung adenocarcinoma; LUSC: Lung squamous cell carcinoma; PAAD: Pancreatic adenocarcinoma; PRAD: Prostate adenocarcinoma.</p>