ol0600988_si_001.pdf (4.92 MB)
Oxidation of gem-Borylsilylalkylcoppers to Acylsilanes with Air
journal contribution
posted on 2006-03-16, 00:00 authored by Junichi Kondo, Hiroshi Shinokubo, Koichiro Oshima1-Boryl-1-silylalkylcoppers react with molecular oxygen in the presence of pyridine to afford acylsilanes efficiently. The one-pot process
consists of two reactions: alkylation of 1-boryl-1-chloro-silylmethyllithium with Grignard reagents in the presence of copper(I) cyanide and
aerobic oxidation of the alkylcopper species. This procedure enables us to access the divergent synthesis of acylsilanes.