Overview of detailed intermolecular interactions governed by ATP and NLRP<sup>NACHT</sup> models.

<p>The NLRP<sup>NACHT</sup> models are displayed in cartoon; ATPs are visualized in light blue ball-sticks and the residues interacting within 5Å of ATP are visualized in white stick model. The black dotted lines represent the intermolecular polar contacts. The key interacting residues (of proposed ATP-binding motifs) are presented in bold font and colored based on their physicochemical parameters.</p>