jo5b00274_si_002.cif (1.78 MB)
One-Pot Sonogashira Coupling–Cyclization toward Regioselective Synthesis of Benzosultams
dataset
posted on 2015-04-17, 00:00 authored by Sudarshan Debnath, Shovan MondalA one-pot
method for the Sonogashira coupling and cyclization of 2-bromobenzenesulfonamides
and terminal alkynes is presented. This method allows access to a
variety of substituted benzosultams regioselectively in excellent
yields. The reasons for regioselectivity are interpreted through density
functional theory (DFT) studies.