Novel BODIPY-Based
Fluorescence Turn-on Sensor for Fe3+ and Its Bioimaging
Application in Living Cells

Sui, Binglin; Tang, Simon; Liu, Taihong; Kim, Bosung; Belfield, Kevin D.

doi:10.1021/am506262u.s001

am506262u_si_001.pdf (8.11 MB)

Novel BODIPY-Based Fluorescence Turn-on Sensor for Fe³⁺ and Its Bioimaging Application in Living Cells

journal contribution

posted on 2014-11-12, 00:00 authored by Binglin Sui, Simon Tang, Taihong Liu, Bosung Kim, Kevin D. Belfield

A novel boron-dipyrromethene (BODIPY) based fluorescence turn-on sensor for detecting Fe³⁺ in aqueous media is reported with 23-fold fluorescence enhancement. The sensor is comprised of a combination of BODIPY fluorophore and a new Fe³⁺-recognizing cryptand that exhibits high selectivity, sensitivity, and reversibility toward Fe³⁺ detection. Cell imaging studies demonstrate that this sensor is capable of sensing Fe³⁺ in living cells.