jo8b00016_si_001.pdf (3.8 MB)
Nickel-Catalyzed C(sp3)–H Arylation of Diarylmethane Derivatives with Aryl Fluorides
journal contribution
posted on 2018-01-31, 00:00 authored by Jie Li, Chen Wu, Bihui Zhou, Patrick J. WalshA novel
nickel-catalyzed C(sp3)–H arylation with
nonactivated aryl fluorides is reported. The use of 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene
(IMes) as a ligand was found to be critical to the success of the
reaction. This new method enables the synthesis of a wide range of
triarylmethane derivatives.