New phenolic acids from <i>Salvia yunnanensis</i> C.H.Wright

<p>Two new phenolic acids, ethyl <i>pro</i>-lithospermate (<b>1</b>), <i>n</i>-butyl <i>pro</i>-lithospermate (<b>2</b>) were isolated from <i>Salvia yunnanensis</i> C.H.Wright, along with nineteen known compounds (<b>3–21</b>). The structures of the isolated compounds were elucidated on the basis of extensive spectrometry and by comparing their physical and spectroscopic data to the literature. Among them, compounds <b>11</b>, <b>12</b> and <b>14–16</b> were firstly isolated from <i>S. yunnanensis</i> C.H.Wright. Some of the isolated compounds were evaluated for their neuroprotection. Compounds <b>10–12</b> showed significant neuroprotective effects in PC12 cells and compounds <b>1</b>, <b>4–7</b> displayed moderate neuroprotective effects.</p>