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New dihydrophenanthrenes from Dendrobium infundibulum

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journal contribution
posted on 2018-03-23, 11:04 authored by Salinee Na Ranong, Kittisak Likhitwitayawuid, Wanwimon Mekboonsonglarp, Boonchoo Sritularak

Two new dihydrophenanthrenes, dendroinfundin A (1) and dendroinfundin B (2) were isolated from the whole plant of Dendrobium infundibulum, together with 7 known compounds (39). The structures of the new compounds (1 and 2) were established on the basis of their spectroscopic data. All of the isolates were evaluated for their α-glucosidase and pancreatic lipase inhibitory activities. Batatasin III (5) and dendrosinen B (9) showed strong α-glucosidase inhibitory activity. Dendrosinen B (9) also exhibited appreciable pancreatic lipase inhibitory effect.

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