ja068119g_si_001.pdf (834.77 kB)
New, Chiral Phase Transfer Catalysts for Effecting Asymmetric Conjugate Additions of α-Alkyl-α-cyanoacetates to Acetylenic Esters
journal contribution
posted on 2007-02-07, 00:00 authored by Xisheng Wang, Masanori Kitamura, Keiji MaruokaA new, chiral phase transfer catalyst has been designed for the development of a general and useful procedure on the hitherto unknown, asymmetric conjugate additions of α-substituted-α-cyanoacetates to acetylenic esters with high enantioselectivity and moderate E/Z selectivity.