Nanoparticles Conjugated with Photocleavable Linkers
for the Intracellular Delivery of Biomolecules

Jiménez-Balsa, Adrián; Pinto, Sandra; Quartin, Emanuel; Lino, Miguel M.; Francisco, Vitor; Ferreira, Lino

doi:10.1021/acs.bioconjchem.7b00820.s001

bc7b00820_si_001.pdf (6.01 MB)

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

journal contribution

posted on 2018-04-13, 18:19 authored by Adrián Jiménez-Balsa, Sandra Pinto, Emanuel Quartin, Miguel M. Lino, Vitor Francisco, Lino Ferreira

We report the synthesis and characterization of phototriggerable polymeric nanoparticles (NPs) for the intracellular delivery of small molecules and proteins to modulate cell activity. For that purpose, several photocleavable linkers have been prepared providing diverse functional groups as anchoring points for biomolecules.