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Nanoparticle Based Photoacoustic Treatment of Cancer

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thesis
posted on 2019-10-15, 23:12 authored by SUDARAKA MALLAWA ARACHCHI
Cancer afflicts a compelling portion of the worldwide population and modern treatment modalities are tainted with myriads of debilitating side-effects. Conceptual nano-medicine modalities such as 'cellular hyperthermia' shed hope on a cancer averted future. However, the required precise control of thermal emission from nano-particle structures remains an open challenge. This thesis investigates utilizing 'super-radiance' to achieve this task. Structured nano-particle emitter assemblies (quantum-dot ring and buckminsterfullerene) are analysed using a quantum-electrodynamics framework and validated using tissue model simulations. The results indicate that superradiance can be used to successfully generate a precise thermal energy pulse to achieve cancer hyperthermia requirements.

History

Campus location

Australia

Principal supervisor

Malin Premaratne

Year of Award

2019

Department, School or Centre

Electrical and Computer Systems Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering