figshare
Browse
Fig 6.tif (628.39 kB)

Migration distance of MSCs over the duration of the experiment.

Download (628.39 kB)
figure
posted on 2017-09-08, 18:15 authored by Siwan Park, Hwanseok Jang, Byung Soo Kim, Changmo Hwang, Gi Seok Jeong, Yongdoo Park

Blue dots in the collagen matrix indicate the locations of nuclei of MSCs (a) Control (b) SDF-1α condition. *p>0.05 (c) AMD3100-treated condition. *p>0.05 (d) Y-27632-treated condition. *p<0.05 (e) NSC23766-treated condition. *p<0.05 (f) RFP-expressing endothelial monolayer confluent to the collagen matrix. RFP-expressing ECs are distinguishable from MSCs. (g) Average migration distance of individual MSCs toward or away from the SDF-1α gradient. Graph bars from top to bottom; Control, SDF-1α, AMD3100, Y-27632, NSC23766. Purple and red fluorescence represents endothelial cells. The monolayer near the collagen matrix is shown in purple because of the higher population of ECs along the Z-axis. Orange triangle represents the presence of SDF-1α gradient. F-test was used to compare the average migration of each conditions with the control group. *p<0.05 represents significant variance difference while *p>0.05 represents no significant variance difference. One-way ANOVA analysis for finding inequality group showed *p<0.05.

History