Method for minimizing disturbances in circadian rhythms of bodily performance and function

Disturbances in circadian rhythms of bodily performance and function, as may occur for example in transfer of work patterns from day to night-shift, or rapid crossing of several time zones in an aircraft ("jet lag") are treated by administration of melatonin. Alleviation or prevention of ill effects associated with disturbance of circadian rhythms is achieved by administration of melatonin in specified ways which are varied to suit particular needs and circumstances.