MOESM6 of The availability of the embryonic TGF-β protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis
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posted on 2016-06-17, 05:00 authored by Maria Oliveira-Nunes, Suzana Assad Kahn, Ana Oliveira Barbeitas, Tania Spohr, Luiz Dubois, Grasiella Ventura Matioszek, William Querido, Loraine Campanati, José Brito Neto, Flavia Lima, Vivaldo Moura-Neto, Katia CarneiroAdditional file 6: Figure S6. Nodal mostly co-localizes to Rab7 and Rab11 in more differentiated GBM cells and in primary cultures. (a) Pearson’s coefficient of relative amount of co-localization of endosomal markers/Nodal in U87MG-O and U87MG cell cultures (quantification of average across three separate fields, each containing an average of three to four spheroids—OB1 cells—or 20 to 30 cells—differentiated OB1 cells). (b) Pearson’s coefficient of relative amount of co-localization of endosomal markers/Nodal in GBM011 cells (quantification of average across three separate fields, each containing an average of 20–30 cells). Data means are ± SD. ***P < 0.001 by two-way ANOVA for repeated measures followed by Tukey’s test for correction of the P value.
