12977_2017_342_MOESM5_ESM.tif (942.87 kB)
MOESM5 of DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas
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posted on 2017-03-17, 05:00 authored by Martina Benešová, Kateřina Trejbalová, Denisa Kovářová, Zdenka Vernerová, Tomáš Hron, Dana Kučerová, Jiří HejnarAdditional file 5: Figure S3. Splicing efficiency of ERVWE1 and ERVFRDE1. Efficiency of splicing of the full-length ERVWE1 and ERVFRDE1 RNAs into the syncytin-1 and synctytin-2 mRNAs in seminomas and non-seminomas is depicted. The data were taken from the RT-qPCR analysis of the ERVWE1 and ERVFRDE1 expression (Figs. 2, 3). Each dot represents the efficiency of splicing in the analyzed sample. Median with interquartile range is depicted. Significance was assigned as follows: **** for P-values < 0.0001, *** for P-values <0.001.