12935_2016_300_MOESM4_ESM.tif (346.12 kB)
MOESM4 of Weight loss reduces basal-like breast cancer through kinome reprogramming
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posted on 2016-04-01, 05:00 authored by Yuanyuan Qin, Sneha Sundaram, Luma Essaid, Xin Chen, Samantha Miller, Feng Yan, David Darr, Joseph Galanko, Stephanie Montgomery, Michael Major, Gary Johnson, Melissa Troester, Liza MakowskiAdditional file 4. Kinome analysis revealed dramatic regulation of kinases by HFD and diet-induced weight loss. a. HFD (60 %-fed) mammary gland kinase activity of greater than 1.5 or less than 0.5 fold compared to 10 %-fed is presented. b. Weight loss (60–10 %-fed) mammary gland kinase activity of greater than 1.25 or less than 0.5 fold compared to 10 %-fed is presented. In b, no error bar is present in pooled samples when kinases were down-regulated below level of detection and only 1 run detected activity.
