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MOESM4 of B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy

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posted on 2017-01-13, 05:00 authored by John Beausang, H. Fan, Rene Sit, Maria Hutchins, Kshama Jirage, Rachael Curtis, Edward Hutchins, Stephen Quake, Julie Yabu
Additional file 4. Change in class-switched isotype abundance and mutation frequency following rituximab and transplantation versus sampling interval. a and b. There were no significant differences between samples collected before or after 40 days (dashed line) following rituximab for either the change in class-switched isotype abundance (a) or mutation frequency (b). c. After transplantation, two samples with an increase in class-switched isotype fraction but otherwise no significant effects due to sampling interval. d. The change in class-switched mutation frequency following transplantation is not affected by sampling interval.

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National Institute of Allergy and Infectious Diseases

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