MOESM3 of Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma

Additional file 3: Figure S2. Global ubiquitinated histone 2A (uH2A), the hallmark of Bmi1-mediated repressive chromatin structures and transcriptional silencing, is significantly downregulated upon PTC-209 treatment (10 ΟM, 48 h). The representative images of western blot are shown.