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MOESM1 of Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms

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posted on 2017-03-09, 05:00 authored by Anna Aguiar, Flávio Figueiredo, Patrícia Neuenfeldt, Tony Katsuragawa, Bruna Drawanz, Wilson Cunico, Photini Sinnis, Fidel Zavala, Antoniana Krettli
Additional file 1: Table S1. Inhibition of Plasmodium gallinaceum sporogony by PQ-TZ derivatives in Aedes mosquitoes blood fed 6 h after oral treatment (6 h) with one compound dose in relation to control mosquitoes fed in the same chicken before treatment (0 h). Table S2. Inhibition of Plasmodium berghei sporogony by PQ-TZ derivatives in Anopheles mosquitoes blood fed 2 h after oral treatment (2 h) with one dose of each compound in relation to mosquitoes blood fed in the mouse before drug treatment (0 h). Figure S1. Plasmodium berghei liver parasite burden 42 h after intravenous inoculation with sporozoites, measured by quantitative PCR in mice treated with PQ-TZ.

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Centro Nacional de Pesquisa e Desenvolvimento

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