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MOESM1 of Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model

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posted on 2016-09-06, 05:00 authored by Paktiya Teja-Isavadharm, Duangsuda Siriyanonda, Maneerat Rasameesoraj, Amporn Limsalakpeth, Nitima Chanarat, Natthasorn Komcharoen, Peter Weina, David Saunders, Montip Gettayacamin, R. Scott Miller
Additional file 1. The concentration–time profiles as measured by HPLC-ECD following intravenous artelinate (lysine salt) 11.8 mg/kg in healthy (n = 10) and P. coatneyi infected rhesus monkeys (n = 8). Values are mean and 95 % confidence interval of concentration in μmole L−1.

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    Malaria Journal

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    Keywords

    Monkey malariaArtelinicArtelinateArtesunatePharmacokineticsPharmacodynamicsParasite clearance

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