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MOESM17 of p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

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posted on 2018-10-13, 05:00 authored by Kun Tian, Emyr Bakker, Michelle Hussain, Alice Guazzelli, Hasen Alhebshi, Parisa Meysami, Constantinos Demonacos, Jean-Marc Schwartz, Luciano Mutti, Marija Krstic-Demonacos
Additional file 17: Figure S2. TP53 protein is stabilized by DNA damage in Mero-14 cells. (A) Mero-14 cells were untreated or treated with etoposide (20 µM) for 24 h, after which cells were lysed and protein harvested and subjected to Western blotting using antibodies against TP53 and actin. (B) ImageJ quantification of TP53 expression in Mero-14 cells following etoposide treatment. (C) Sequence alignment of the coding sequence of the TP53 gene (exons 1–11) from Mero-14 cell line.

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