MOESM11 of Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia

Additional file 11. Network representation of overlapping gene sets associated with ART-R subpopulations (set of 265 genes) and the ART-S subpopulation KH1.2 common resistance background (set of 168 genes). The networks for the two gene sets based on co-expression data are recovered from STRING v10. The edges connecting the genes, have the co-expression evidence score greater than 0.5. The nodes and edges in “red” color represent the interaction network based on coexpression for ART-R subpopulations gene set. The nodes and edges in “white” color represent the interaction network based on coexpression for ART-S sunpopulation KH1.2 common resistance background genes set. For the ART-R subpopulation specific genes set, out of the 265 genes only 173 genes are used for overlap and for the KH1.2 common resistance background genes set, out of 168 only 113 genes are used for overlap. Other genes (nodes) are removed either because of no interactions (before/after overlap) or STRING confidence score below 0.5. The representation of overlapping coexpression network is done in Cytoscape v3.2.1 using the DyNet Analyzer plugin.