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Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice - Fig 9

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posted on 2019-04-03, 20:05 authored by Manuel Garcia-Jaramillo, Melinda H. Spooner, Christiane V. Löhr, Carmen P. Wong, Weijian Zhang, Donald B. Jump

Western diet effects on the expression of enzymes involved in complex lipid synthesis (A) and TG catabolism (B). Transcript abundance was quantified as described above. Results are expressed as mRNA abundance, Fold Change; mean ± SEM, N = 7–8 samples, *, FDR < 0.05 versus the RD46 group. [A: Gly Kin, glycerokinase; Gpatm, glycerophosphate acyltransferase-mitochondrial; Dgat, diacylglycerol acyl transferase; LpCat, lysophosphatidyl choline acyltransferase; Crls, cardiolipin synthase; Taf, tafazzin; SpTlc, serine palmitoyl transferase long chain; Sgms, sphingomyelin synthase]; [B: Atgl, adipocyte triglyceride lipase, Ces1g, carboxyesterase-1g; Tgh, triglyceride hydrolase/Ces3].

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