L* footprint on RNase L.

<p>Highlighting of residues that were mapped in ANK R1 and R2 as components of the L* footprint on RNase L (in orange). The two RNase L protomers are represented in gray and blue, 2-5A molecules are represented in pink and RNA substrate and ATP mimetics are represented by green dots. (Crystal structure of dimeric human RNase L; [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006989#ppat.1006989.ref045" target="_blank">45</a>]; PDB 4OAV). Images were generated using the PyMOL Molecular Graphics System, Version 1.7, Schrödinger, LLC.</p>