Fig 3.tif (189.49 kB)
LPS stimulation of THP-1 cells results in FAMIN upregulation.
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posted on 2016-12-13, 18:57 authored by Ghazaleh Assadi, Liselotte Vesterlund, Ferdinando Bonfiglio, Luca Mazzurana, Lina Cordeddu, Danika Schepis, Jenny Mjösberg, Sabrina Ruhrmann, Alessia Fabbri, Vladana Vukojevic, Piergiorgio Percipalle, Florian A. Salomons, Jurga Laurencikiene, Leif Törkvist, Jonas Halfvarson, Mauro D’Amato(A) qRT-PCR analysis of LACC1 mRNA expression in THP-1 cells stimulated with PMA and LPS. (B) WB analysis of FAMIN protein expression in THP-1 cells stimulated with PMA and LPS. Relative intensity (RI) from densitometric analysis is reported. Data are representative of three independent experiments. Abbreviation; UN: unstimulated control.
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Gene-set enrichment analysesLACC 1 expressionflow cytometry analysesPCRreactive oxygen species productionsmall-interference RNA knockdownacid metabolism-immune nexusorganelle endomembrane structuresPPAR ligands downregulated FAMIN expressionperoxisome proliferator-activated receptorselucidating LACC 1plasmacytoid dendritic cellsLACC 1LACC 1 functiontissueLACC 1 co-expression signaturesmechanismResults FAMIN expressionTHP
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