ppat.1006912.g004.tif (1.61 MB)
KSHV and RRV mutants.
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posted on 2018-02-12, 18:46 authored by Anna K. Großkopf, Armin Ensser, Frank Neipel, Doris Jungnickl, Sarah Schlagowski, Ronald C. Desrosiers, Alexander S. HahnA List of bacmid-derived recombinant viruses generated for this study. B Schematic representation of mutations introduced into gH/gL. C SLK cells infected with wt or mutant KSHV or RRV.
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Eph family receptor tyrosine kinasesKSHV strainsgHprotein-protein interactionsoncogenic virusEph-binding residuesEph-binding-negative RRV mutantsrhesus monkey rhadinovirusnonhuman primatesN-terminal domainsequence analysisRRV glycoprotein HB-cell malignancieslog orderRRV gLEph family receptor-binding motifentry mediatorsInhibition experimentscell typeshost factorsgL expressioncell type-specific useEph-interaction motif
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