Fig 3.tif (519.39 kB)
Isothermal titration calorimetry data.
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posted on 2017-10-31, 17:47 authored by Michelle P. Christie, Shu-Hong Hu, Andrew E. Whitten, Asma Rehman, Russell J. Jarrott, Gordon J. King, Brett M. Collins, Jennifer L. MartinThe raw data (upper part of each panel) and integrated normalized data (lower part of each panel) are shown from ITC experiments between HMunc18c or Munc18a-His and cognate/non-cognate Sx partners.
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non-cognate Munc 18c Syntaxin 1Syntaxin 4. Munc 18aNeuronal Munc 18aSNARE protein SyntaxinRevisiting interaction specificitySNARE interaction specificitySyntaxin N-peptide interactionMunc 18cMunc 18aRegulatory Munc 18 proteinsSNARE proteinspartner SNARE Syntaxinsspatiotemporal fusion eventsMunc 18c bind SyntaxinsSNARE partners SNAP 25binding Syntaxin 4binding interactionsadipocyte Munc 18 membrane fusionSyntaxin 1 N-peptideVAMPSyntaxin 1Syntaxin 4adipocyte Munc 18c
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