gnpl_a_1490902_sm8008.pdf (1.36 MB)
Isolation and identification of new prenylated acetophenone derivatives from Acronychia oligophlebia
journal contribution
posted on 2018-10-31, 13:36 authored by Qian-Wen Niu, Neng-Hua Chen, Zhong-Nan Wu, Ding Luo, Ying-Ying Li, Yu-Bo Zhang, Qing-Guo Li, Yao-Lan Li, Guo-Cai WangThree new prenylated acetophenone derivatives, acronyculatin P (1), acronyculatin Q (2), and acronyculatin R (3) were isolated from the leaves of Acronychia oligophlebia. Their structures were identified by extensive analyses of spectroscopic data (IR, UV, ESI-HRMS, 1D and 2D NMR) and comparison with the literatures. In addition, the cytotoxic activity against MCF-7 cells of the compounds were evaluated by the MTT assay and the IC50 values were 56.8, 40.4 and 69.1 μM, respectively.