ol9903281_si_001.pdf (160.48 kB)
Iodomethane Oxidation by Dimethyldioxirane: A New Route to Hypoiodous Acid and Iodohydrines
journal contribution
posted on 1999-12-03, 00:00 authored by Gregorio Asensio, Cecilia Andreu, Carmen Boix-Bernardini, Rossella Mello, María Elena González-NuñezThe oxidation of iodomethane with dimethyldioxirane allows the generation of stable neutral solutions of hypoiodous acid in the absence of
any trapping agent for iodide anion. Hypoiodous acid is trapped in situ by addition to representative olefins to give iodohydrines in good
yields. The stereochemical study of the products shows the anti-stereospecific nature of the iodohydroxylation reaction.