ol101154h_si_001.pdf (4.61 MB)
Improved Arene Fluorination Methodology for I(III) Salts
journal contribution
posted on 2010-08-06, 00:00 authored by Bijia Wang, Linlin Qin, Kiel D. Neumann, ShriHarsha Uppaluri, Ronald L. Cerny, Stephen G. DiMagnoThe use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to “scale down” to the conditions used typically for radiotracer synthesis.